Endocrine Abstracts

Introduction: Central diabetes insipidus (CDI) is a rare but potentially dangerous dysregulation of the water balance secondary to an arginine vasopressin (AVP) deficiency. Diabetes insipidus may have different manifestations in children compared to adults. CDI is more common in children than nephrogenic diabetes insipidus.Methods: A retrospective study of eight patients collected in the pediatric department of Mahdia.Results: The ...

Introduction: Fasting during the month of Ramadan is the most observed religious practice by Muslims. Diabetes is one of the condition that exempt Muslims from fasting because of the risk of complications. The International Diabetes Federation states that high-risk patients ‘should not fast’. The objective of this study was therefore to evaluate the daily food intake during the month of Ramadan in non-fasting patients with diabetes in order to detect diet mistakes ma...

Background: X-linked adrenoleukodystrophy (X-ALD) is the most common peroxisomal disorder. The clinical spectrum in males with X-ALD ranges from isolated adrenal insufficiency (AI) and slowly progressive myelopathy to devastating cerebral demyelination. Gitelman syndrome (GS) is a rare autosomal recessive inherited tubular disease which is caused by mutation in the SLC12A3 gene. It is characterized by hypokalemic alkalosis with hypomagnesemia and hypocalciuria. We report the a...

Background: Mucormycosis, also known as black fungus, is a rare, aggressive, locally invasive, and life-threatening fungal infection that can occur in healthy individuals but that is more frequently seen in immuno-compromised patients especially in diabetics in the context of diabetic keto-acidosis. Early diagnosis is a key for good prognosis.Case Presentation: We report the case of a 66-year-old Tunisian male, with a history of uncontrolled type 2 diabe...

Background: HAIR-AN, a syndrome of hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN), is a specific subphenotype of polycystic ovary syndrome, and it is seen in almost 5% of all women with hyperandrogenism. We report the case of a HAIR-AN which posed a diagnostic challenge in a 16-year-old girl.Case Presentation: A 16-year-old girl was referred by her pediatrician to the Endocrinology Department for exploration of primary ameno...

Introduction: During adrenal insufficiency (AI), glucocorticoid treatment is supposed to be neutral on the metabolic parameters of patients. However, recent data from the literature report that this corticosteroid replacement therapy increases the metabolic risk. The aim of our work was to determine the metabolic and cardiovascular impact of hydrocortisone (HC) replacement therapy during peripheral AI.Patients and methods: This was a descriptive and anal...

Introduction: The treatment of adrenal insufficiency (AI) is based on long-term glucocorticoid substitution. Hydrocortisone (HC) is the most commonly used substitution molecule. The aim of our work was to determine the long-term bone impact of patients with peripheral AI.Patients and methods: This is a descriptive and analytical study involving 77 patients with peripheral IS (66 women and 11 men), all treated with HC. For each patient, we determined the ...

Introduction: Diabetes distress (DD) refers to the emotional burdens and worries, often hidden, that are part of the spectrum of the patient experience when managing a chronic and demanding disease like diabetes. The objective of this work was to determine the prevalence of DD and its clinical determinants in type 2 diabetic patients.Patients and methods: Cross-sectional study conducted on 92 type 2 diabetic patients who consulted on an outpatient basis ...

Introduction: Medication Adherence (MA) is the extent to which patients follow medical instructions. Poor MA is frequently encountered in the majority of chronic diseases, including diabetes. The aim of our study was to evaluate MA in patients with poorly controlled type 2 diabetes mellitus (T2DM).Patients and methods: We conducted a cross-sectional study over a period of 2 months, including patients with poorly controlled T2DM, followed at the endocrino...

Introduction: Nutrition is a cornerstone of the adequate management of Type 2 diabetes mellitus (T2DM). The aims of our work are to evaluate the degree of observance of dietary rules in T2DM patients, and the factors that influence this observance.Methods: Cross-sectional study including 84 type 2 diabetic patients followed up in the outpatient endocrinology department of Taher Sfar university hospital from September to November 2021. The data was collec...